The article proposes a methodological approach to identifying strategic priorities for the diversification of the Mangystau Region's economy. The study is based on systemic and institutional approaches, a review of scientific literature, sectoral concentration indicators, and a multicriteria procedure for project selection. Key areas for diversification are identified, including industrial cooperation, logistics, tourism, resource-saving technologies, and entrepreneurship. The proposed methodological framework integrates the assessment of the sectoral structure with the evaluation of infrastructure constraints, implementation mechanisms, and monitoring of the quality of economic growth. The study is conceptual and methodological in nature; quantitative assessments of the effectiveness of economic policies require further empirical validation.

economic diversification, Mangystau Region, structural transformation, regional economy, strategic priorities, investment policy, economic mechanisms.